Ans: The top attractions to visit in Florence are: Gallerie Degli Uffizi, Piazzale Michelangelo, Galleria dell'Accademia, Basilica of Santa Croce, Duomo - Cattedrale di Santa Maria del Fiore etc.
Ans: For an art lover, Florence is a real paradise.
Ans: The fastest way to get from Rome to Florence is by taking a high-speed train from Rome Termini or Tiburtina station into Florence Santa Maria Novella Station. The fast trains take 1.5 hours to get from central Rome to central Florence. The fast trains go around every 20-30 minutes all day from about 6am-9pm.
Ans: Rome and Florence are perfectly safe - much safer than most large US cities.
Ans: Florence is a small city and generally a safe place where street-smart rules apply. Avoid wandering around town alone, late at night, particularly in the Santa Maria Novella area. Stick to main roads and avoid narrow back alleys.